News from dookie

Help me customize my OS X keyboard for my strained, RSI-inflicted fingers. A touch of RSI turned me into a left handed mouser a few years back. No major hassles on the conversion. Being a leftie is cool. However, I`d like to relocate frequently used OS X hotkeys, such as "Command-copy" "Command-paste" and "Quit," to keys on the right side of my QWERTY keyboard. The key customization program Keyboard Maestro, while it has its benefits, can`t handle these three commands (and many others). And OS X`s Keyboard ` Mouse preferences would require customization for each individual app, and don`t seem to be workable with apps like Firefox, which "overrides" customization with its builtin hotkeys (in my experience). Are there any third-party programs that enable simple, works-for-all-apps customization of OS X hotkeys? (Searches on Google, Apple forums, and AskMefi have failed me.) Even more radical, perhaps: can the OS X keyboard *itself* be customized? I`d love to place the backspace key on the caps lock key, as I did once via xmodmap on Linux.